Research Scientist en Experimental — Barcelona

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Understanding the dynamic three-dimensional spatial patterns of gene expression is essential for elucidating the mechanisms that drive tissue development and disease. To address this challenge, the Sharpe lab developed Cell 3D Positioning by Optical Encoding (C3PO) , an innovative methodology that preserves three-dimensional positional information from intact biological tissues prior to dissociation. By embedding spatial coordinates directly within cells using controlled optical encoding, C3PO …

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